• My Basket 0

    Badrilla Default welcome msg!

    Back

    SERCA2a pAb serum

    $325.00

    In stock

    Product code: A010-20
    Unit Size: 20 μl

    Highly specific, well validated polyclonal antiserum to SERCA2a

     SERCA2a is a Ca2+ pump located in the sarcoplasmic reticulum of cardiac and slow-twitch skeletal muscle. The enzyme transports Ca2+ from the cytoplasm into the SR using the hydrolysis of ATP as the energy source for this reaction. Two Ca2+ are transported for each ATP hydrolysed.  This Ca2+ transport is the principal means of muscle relaxation in cardiac and slow-twitch skeletal muscle. The activity of SERCA2a is moderated by its interaction with phospholamban. SERCA2a is one isoform of SERCA2: this isoform differs from SERCA2b and SERCA2c at the extreme carboxy terminus only.  Antibody A010-20 recognises the C-terminal sequence which distinguishes SERCA2a from SERCA2b and SERCA2c. 

    Tested applications: Western Blot (1:5000 dilution). Species recognition: The antibody reacts with SERCA2a from human, rat, mouse, rabbit, canine, and bovine species.

    Description Lyophilised Rabbit polyclonal serum containing IgG antibody specific to SERCA2a
    Immunogen Synthetic peptide (C-LEPAILE997) corresponding to amino acids at the extreme C-terminus of SERCA2a
    Isotype IgG
    Purification Raw serum
    Species reactivity The antibody recognises SERCA2a and binding is blocked in the presence of a peptide containing the epitope. The antibody reacts with SERCA2a from human, rat, mouse, rabbit, canine, and bovine species.
    Tested applications WB, ELISA and IHC microscopy
    Recommended dilution WB 1:5000
    Optimization Optimal dilutions to be determined by end user
    Storage Lyophilised antibody is stable at 4°C when stored with desiccant. Reconstitute lyophilised powder in 20 µl of 18 MΩ H2O, aliquot and store frozen at -80°C for 1 year. Avoid freeze - thaw cycles.
    Storage Lyophilised: 4 °C. Reconstituted:-80 °C
    Datasheet A010-20 Lot 0210-06



    A010-20 Lot 0814-01

    MSDS A010-20

    Regulatory statement Product for research use only. Not intended for diagnostic or therapeutic use.

    Contact Us

    Leeds Innovation Centre

    103 Clarendon Road

    Leeds LS2 9DF

    United Kingdom

    +44 (0)7801 730618

    info@badrilla.com

    Useful Links

    .

    DISCLAIMER: Products for research use only (RUO) and are not intended for diagnostic or therapeutic use.

    Badrilla Newsletters

    Sign up for Badrilla newsletters today and receive twice-monthly informative emails relating to cardiovascular research.
    Badrilla enewsletter sign up