• My Basket 0

    Badrilla Default welcome msg!


    SERCA2a pAb serum


    In stock

    Product code: A010-20
    Unit Size: 20 μl

    Description: Highly specific, well validated Polyclonal anti-sera to SERCA2a (anti-SERCA2a)

    Background: SERCA2a is a Ca2+ pump located in the sarcoplasmic reticulum of cardiac and slow-twitch skeletal muscle. The enzyme transports Ca2+ from the cytoplasm into the SR using the hydrolysis of ATP as the energy source for this reaction. Two Ca2+ are transported for each ATP hydrolysed.  This Ca2+ transport is the principal means of muscle relaxation in cardiac and slow-twitch skeletal muscle. The activity of SERCA2a is moderated by its interaction with phospholamban. SERCA2a is one isoform of SERCA2: this isoform differs from SERCA2b and SERCA2c at the extreme carboxy terminus only.  Antibody A010-20 recognises the C-terminal sequence which distinguishes SERCA2a from SERCA2b and SERCA2c. 

    Tested Applications: Western Blot (1:5000 dilution)

    Antibody Form:  Lyophilised Rabbit anti-serum (IgG).

    Species Recognition: The antibody reacts with SERCA2a from human, rat, mouse, rabbit, canine, and bovine species

    Full Publication list: 20 papers


    Selected Publications:

    Carbon monoxide exposure enhances arrhythmia after cardiac stress: involvement of oxidative stress. 

    André, L., Gouzi, F., Thireau, J., Meyer, G., Boissiere, J., Delage, M., Abdellaoui, A., Feillet-Coudray, C., Fouret, G., Cristol, J.P., et al. (2011). Basic Res Cardiol 106, 1235-1246.

    Aromatase deficiency confers paradoxical postischemic cardioprotection.

    Bell, J.R., Mellor, K.M., Wollermann, A.C., Ip, W.T., Reichelt, M.E., Meachem, S.J., Simpson, E.R., and Delbridge, L.M. (2011).  Endocrinology 152, 4937-4947.

    Storage Lyophilised: 4 °C Reconstituted:-80 °C
    Epitope/Isoform Alignment No
    Epitope/Species Alignment

    Ep/Sp Alignment

    Data Sheet


    (PDF 219 kB)

    A010-20 lot: 1012-10

    (PDF 499 kB)



    Write Your Own Review

    Only registered users can write reviews. Please, log in or register

    Contact Us

    Leeds Innovation Centre

    103 Clarendon Road

    Leeds LS2 9DF

    United Kingdom

    +44 (0)7801 730618