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    These antibodies have been fully validated by western blotting, and in many cases, tested in immunoflourescence, ELISA and immunoprecipitation assays. In addition to antibodies against cardiovascular targets, we source and re-validate highly specific antibodies from academic leaders. Our aim is to provide products that work first time in the applications you deploy, which accelerate the progress of your research, and which satisfy your expectations in every way.

    Highly specific monoclonal and polyclonal antibodies are pivotal to the success of programs of research. Successful application of each antibody product in Western blot (WB), immunofluorescence microscopy (IF), and functional assays is indicated where we have direct evidence. Antibodies may prove suitable for use in additional formats of immunoassay.

    Items 11 to 20 of 67 total

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    1. CAPTUREome™ S-Palmitoylated Protein Kit

      $499.00
      Product code: K010-311

      The Badrilla CAPTUREomeTM S-Palmitoylated protein kit is a simple and easy way of determining whether your protein of interest is post translationally modified with a palmitate group. The assay is based on the acyl-RAC (resin assisted capture) method and facilitates, with four simple steps – Block, Cleave, Capture and Analysis -  determination of protein palmitoylation.

      Kit highlights

      • Enables capture of S-palmitoylated proteins.
      • Kit designed to process 4 x 5 biological samples with paired negative controls (i.e. 40 samples in total).
      • Convenient stopping point after blocking treatment.
      • Assay suitable for downstream SDS-PAGE, western blot or mass spectrometry analysis.
      Learn More
    2. CAPTUREome™ S-Palmitoylated Protein Mini Kit

      $199.00
      Product code: K010-310

      The new CAPTUREomeTM S-Palmitoylation Mini Kit from Badrilla represents an affordable gateway into the emerging field of palmitoylation research. The Mini Kit, based on acyl RAC (resin assisted capture) technology, enables rapid determination of protein palmitoylation status from as little as 1mg of total cell lysate protein.

      • Competitively priced entry level kit.
      • Enables quick and easy capture of S-palmitoylated proteins from as little as 1mg of total cell lysate protein.
      • Kit designed to process 2 x 3 biological samples with paired negative controls (i.e. 12 samples in total).
      • Convenient stopping point after blocking treatment.
      • Assay suitable for downstream SDS-PAGE, western blot or mass spectrometry analysis.
      Learn More
    3. Dantrolene sodium salt

      $67.00
      Product code: A010-505

      Dantrolene inhibits release of Ca2+ from the sarcoplasmic reticulum (SR) via inhibition of ryanodine receptor (RYR) channels. Learn More

    4. DETECTome™ S-nitrosylated protein kit

      $368.00
      Product code: A010-105
      A convenient and easy-to-use kit incorporating a modification of the “biotin-switch” method to allow for the direct visualisation of S-nitrosylated proteins in whole cells or tissues, as well as by western blot analysis. 
       
      • A modified ‘biotin-switch’ assay
      • Labels all S-nitrosylated sites in sample ('omics')
      • DETECT S-NO proteins in whole cells, tissues or lysates
      • Colourimetric or fluorimetric detection
      • Sufficient reagents for 3 x 20 samples
      Learn More
    5. DPc10 Inactive Peptide

      $158.49
      Product code: A010-515

      DPc10 inactive peptide is a 36-residue peptide that differs from DPc10 (Gly2460-Pro2495, rabbit) at one position (R2475S) and represents the sequence of a known CPVT mutant RYR2 domain. This peptide binds weakly or fails to bind to the DPc10 interface and does NOT affect channel function. It serves as a negative control for research projects using DPc10 peptide.  

      Pack size 200µg.

      Learn More
    6. DPc10 Peptide

      $158.49
      Product code: A010-514

      DPc10 peptide is a 36-residue peptide corresponding to the Gly2460-Pro2495 region of rabbit RyR2. It interacts with RYR2 and provokes abnormal channel activity usually seen in mutant RYR2 channels associated with CPVT. Elevates Ca2+-leak, increases Ca2+-spark activity, is pro-arrhythmic, and provokes hypertrophy in cardiac myocytes.  

      Pack size 200µg.

      Learn More
    7. DPc10 Peptides Sampler Pack

      $480.00
      Product code: A010-518

      Convenient, cost effective sampler pack containing four DPc10 peptide derivatives (200µg each) as follows:

      1. DPc10 Peptide (Cat. A010-514)
      2. DPc10 Inactive Peptide (Cat. A010-515)
      3. Fluorescein DPc10 Peptide (Cat. A010-516)
      4. Fluorescein DPc10 Inactive Peptide (Cat. A010-517)
      Learn More
    8. Epoxomicin

      $257.00
      Product code: A010-512

      Proteasome-specific and highly potent, cell permeable, irreversible inhibitor. Reacts with all three active sites of the proteasome, primarily targets chymotrypsin-like activity.

      Learn More
    9. Erk 1/2 (pThr188) pAb

      $325.00
      Product code: A010-40AP

       Affinity purified Rabbit polyclonal antibody to Erk1/2 phospho threonine 188

      • Tested applications: Western blot (1:1000 dilution)
      • Protein A affinity purified
      • Species Reactivity: peptide aligns with sequence from both Mouse and Human. Threonine 188 is number in relation to the mouse sequence of ERK2.
      • Unit size: 50 µl / µg
      Learn More
    10. Fluorescein DPc10 Inactive Peptide

      $190.18
      Product code: A010-517

      Fluorescein derivative of the DPc10 inactive peptide, a 36-residue peptide that differs from DPc10 (Gly2460-Pro2495, rabbit) at one position (R2475S) and represents the sequence of a known CPVT mutant RYR2 domain. This peptide binds weakly or fails to bind to the DPc10 interface and does NOT affect channel function. It serves as a negative control for research projects using DPc10 peptide.

      Pack size 200µg.

      Learn More

    Items 11 to 20 of 67 total

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    Shop By
    Category
    1. Cardiovascular Targets (21)
    2. Residue Modification (6)
    3. Tag Proteins (7)
    4. Bioactive Peptides (5)
    5. Biochemicals (13)
    Clonality
    1. mAb (8)
    2. pAb (34)
    Phosphorylation site
    1. dephoSer2808 (1)
    2. dual pSer/Thr 68/69 (1)
    3. pSer10 (1)
    4. pSer16 (2)
    5. pSer1928 (1)
    6. pSer197 (1)
    7. pSer2030 (1)
    8. pSer2808 (2)
    9. pSer2814 (2)
    10. pSer38 (1)
    11. pSer63 (1)
    12. pSer68 (1)
    13. pThr17 (2)
    14. pThr188 (1)
    15. pThr286 or 287 (2)
    16. pTyr892 (1)
    17. Thr69 (1)
    Product type
    1. Activator (2)
    2. Antibody (44)
    3. Bioactive peptide (5)
    4. Capture kit (2)
    5. Detection kit (3)
    6. Inhibitor (11)
    Target
    1. AMPK (1)
    2. Calcineurin (1)
    3. CaMKII (4)
    4. Cav1.2 (1)
    5. cMyc (2)
    6. Erk1/2 (1)
    7. GFP (2)
    8. mCherry (2)
    9. mEOS2 (1)
    10. mTor (1)
    11. Nitrotyrosine (3)
    12. Phospholemman (4)
    13. PLN (6)
    14. Proteasome (2)
    15. RyR2 (15)
    16. S-NO (4)
    17. SERCA (3)
    18. SERCA1 (1)
    19. SERCA2a (3)
    20. SERCA2b (2)
    21. V-ATPase (2)
    22. β-Dystroglycan (1)
    23. β2-AR (2)
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    Leeds Innovation Centre

    103 Clarendon Road

    Leeds LS2 9DF

    United Kingdom

    +44 (0)7801 730618

    info@badrilla.com

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    DISCLAIMER: Products for research use only (RUO) and are not intended for diagnostic or therapeutic use.

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