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Company ProfileBadrilla Ltd, founded in 2003, is an established life science company providing high quality products for the molecular cardiovascular researcher located within major pharmaceutical, biotech, and academic establishments worldwide... Read More
Management TeamProfessor Colyer established Badrilla in 2003, combining substantive entrepeneurial experience with a deep understanding of the cardiovascular research field. The company has grown organically, reinvesting revenues into... Read More
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These antibodies have been fully validated by western blotting, and in many cases, tested in immunoflourescence, ELISA and immunoprecipitation assays. In addition to antibodies against cardiovascular targets, we source and re-validate highly specific antibodies from academic leaders. Our aim is to provide products that work first time in the applications you deploy, which accelerate the progress of your research, and which satisfy your expectations in every way.
Highly specific monoclonal and polyclonal antibodies are pivotal to the success of programs of research. Successful application of each antibody product in Western blot (WB), immunofluorescence microscopy (IF), and functional assays is indicated where we have direct evidence. Antibodies may prove suitable for use in additional formats of immunoassay.
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DETECTome™ S-nitrosylated protein kit
$368.00Product code: A010-105A convenient and easy-to-use kit incorporating a modification of the “biotin-switch” method to allow for the direct visualisation of S-nitrosylated proteins in whole cells or tissues, as well as by western blot analysis.- A modified ‘biotin-switch’ assay
- Labels all S-nitrosylated sites in sample ('omics')
- DETECT S-NO proteins in whole cells, tissues or lysates
- Colourimetric or fluorimetric detection
- Sufficient reagents for 3 x 20 samples
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DPc10 Inactive Peptide
$158.49Product code: A010-515DPc10 inactive peptide is a 36-residue peptide that differs from DPc10 (Gly2460-Pro2495, rabbit) at one position (R2475S) and represents the sequence of a known CPVT mutant RYR2 domain. This peptide binds weakly or fails to bind to the DPc10 interface and does NOT affect channel function. It serves as a negative control for research projects using DPc10 peptide.
Pack size 200µg.
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DPc10 Peptide
$158.49Product code: A010-514DPc10 peptide is a 36-residue peptide corresponding to the Gly2460-Pro2495 region of rabbit RyR2. It interacts with RYR2 and provokes abnormal channel activity usually seen in mutant RYR2 channels associated with CPVT. Elevates Ca2+-leak, increases Ca2+-spark activity, is pro-arrhythmic, and provokes hypertrophy in cardiac myocytes.
Pack size 200µg.
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DPc10 Peptides Sampler Pack
$480.00Product code: A010-518Convenient, cost effective sampler pack containing four DPc10 peptide derivatives (200µg each) as follows:
- DPc10 Peptide (Cat. A010-514)
- DPc10 Inactive Peptide (Cat. A010-515)
- Fluorescein DPc10 Peptide (Cat. A010-516)
- Fluorescein DPc10 Inactive Peptide (Cat. A010-517)
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Erk 1/2 (pThr188) pAb
$325.00Product code: A010-40APAffinity purified Rabbit polyclonal antibody to Erk1/2 phospho threonine 188
- Tested applications: Western blot (1:1000 dilution)
- Protein A affinity purified
- Species Reactivity: peptide aligns with sequence from both Mouse and Human. Threonine 188 is number in relation to the mouse sequence of ERK2.
- Unit size: 50 µl / µg
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Fluorescein DPc10 Inactive Peptide
$190.18Product code: A010-517Fluorescein derivative of the DPc10 inactive peptide, a 36-residue peptide that differs from DPc10 (Gly2460-Pro2495, rabbit) at one position (R2475S) and represents the sequence of a known CPVT mutant RYR2 domain. This peptide binds weakly or fails to bind to the DPc10 interface and does NOT affect channel function. It serves as a negative control for research projects using DPc10 peptide.
Pack size 200µg.
Learn More -
Fluorescein DPc10 Peptide
$190.18Product code: A010-516Fluorescein derivative of DPc10 peptide, a 36-residue peptide corresponding to the Gly2460-Pro2495 region of rabbit RyR2. It interacts with RYR2 and provokes abnormal channel activity usually seen in mutant RYR2 channels associated with CPVT. Elevates Ca2+-leak, increases Ca2+-spark activity, is pro-arrhythmic, and provokes hypertrophy in cardiac myocytes.
Pack size 200µg
Learn More -
Green fluorescent protein (GFP, EGFP) pAb epitope purified
$325.00Product code: A010-pGFP-50A fully validated, highly specific, affinity purified rabbit polyclonal antibody to GFP, EGFP, PA-GFP, CFP and YFP
- Suitable for use in Western blot (1:10,000 dilution), IF Microscopy (1:500 - 5000 dilution)
- Lyophilised affinity purified IgG.
- Unit size: 50 μg - enough for 312 blots
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Green fluorescent protein (GFP, EGFP) pAb epitope purified
$70.00Product code: A010-pGFP-5A fully validated, highly specific, affinity purified rabbit polyclonal antibody to GFP, EGFP, PA-GFP, CFP and YFP
- Suitable Western blot (1:10,000 dilution), IF Microscopy (1:500 - 5000 dilution)
- Lyophilised affinity purified IgG
- Unit size: 5 μg - enough for 31 blots
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L-type Ca2+ channel (Cav1.2) (pSer1928) pAb
$599.00Product code: A010-70Polyclonal antibody specific to Ser-1928 phosphorylated Cav1.2 (α1c sub-unit of L-type Ca2+-channel).
- Suitable for use in: IHC Microscopty (1:100 dilution)
- Lyophilised rabbit anti-serum (IgG)
- Species recognition: all mammalian species, when phosphorylated on Ser-1928.
- Unit size: 50 µl
- Category
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- Cardiovascular Targets (20)
- Residue Modification (6)
- Tag Proteins (7)
- Bioactive Peptides (5)
- Biochemicals (3)
- Clonality
- Phosphorylation site
- Product type
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- Antibody (44)
- Bioactive peptide (5)
- Capture kit (2)
- Detection kit (3)
- Inhibitor (3)
- Target
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- Calcineurin (1)
- CaMKII (4)
- Cav1.2 (1)
- cMyc (2)
- Erk1/2 (1)
- GFP (2)
- mCherry (2)
- mEOS2 (1)
- Nitrotyrosine (3)
- Phospholemman (4)
- PLN (6)
- RyR2 (11)
- S-NO (4)
- SERCA (2)
- SERCA1 (1)
- SERCA2a (3)
- SERCA2b (2)
- V-ATPase (1)
- β-Dystroglycan (1)
- β2-AR (2)
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Leeds Innovation Centre
103 Clarendon Road
Leeds LS2 9DF
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DISCLAIMER: Products for research use only (RUO) and are not intended for diagnostic or therapeutic use.
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