Cardiovascular Targets

The excitation-contraction coupling of cardiac muscle is a critical to life in most animals, and errors in E-C coupling contribute to important human diseases (arrhythmia, heart failure, cardiac hypertrophy). Highly specific monoclonal and polyclonal antibodies to proteins critical to cardiac muscle excitation-contraction coupling have been assembled. All of these antibodies have been carefully validated for use in western blotting, in addition, some have also been validated for use in immunofluorescence microscopy and in vitro functional assays. Many of these antibodies recognise the site-specific phosphorylation of target proteins and most have been used in numerous publications in the scientific literature.
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$325.00
Product code: A010-14
Mouse monoclonal antibody to phospholamban.
- Suitable for use in Western blot (1:5000 dilution), IHC Microscopy (1:200 dilution), Ca2+ pump assay (1:500 dilution).
- Lyophilised affinity purified IgG
- Species recognition: all mammalian species
- 25 μg unit size
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$325.00
Product code: A010-21AP
Affinity purified Mouse monoclonal antibody to SERCA isoforms 1/2
- Suitable for use in Western blot (1:2000 dilution), IHC Microscopy (1:50 dilution).
- Lyophilised Protein A affinity purified mouse monoclonal IgG
- Tested on rat tissue, but immunogenic peptide aligns with Mammalian, Avian, Amphibian and Fish SERCA
- Unit size: 50 μl
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$325.00
Product code: A010-22AP
Affinity purified Mouse monoclonal antibody to skeletal muscle SERCA1
- Suitable for use in Western Blot (1:5000 dilution), IHC Microscopy (1:200 dilution)
- Lyophilised Protein A affinity purified mouse monoclonal IgG
- Antibody tested on rat and rabbit tissue, but immunogenic peptide aligns with mammalian species, avian, amphibian and fish
- Unit size: 50 μl
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