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    Cardiovascular Targets

    Cardiovascular Targets

    The excitation-contraction coupling of cardiac muscle is a critical to life in most animals, and errors in E-C coupling contribute to important human diseases (arrhythmia, heart failure, cardiac hypertrophy). Highly specific monoclonal and polyclonal antibodies to proteins critical to cardiac muscle excitation-contraction coupling have been assembled. All of these antibodies have been carefully validated for use in western blotting, in addition, some have also been validated for use in immunofluorescence microscopy and in vitro functional assays. Many of these antibodies recognise the site-specific phosphorylation of target proteins and most have been used in numerous publications in the scientific literature.

    Items 1 to 10 of 15 total

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    1. Phospholamban (PLN, PLB) (pSer16) pAb serum

      $325.00
      Product code: A010-12

      Rabbit polyclonal antibody to phospholamban phospho serine-16.

      • Suitable for use in Western blot (1:5000 dilution)
      • Antibody form: IgG
      • Species recognition: human, mouse, rat, sheep, chicken, bovine, canine, ferret, hamster
      • 25 µl unit size
      Learn More
    2. Phospholamban (PLN, PLB) (pSer16) pAb

      $545.00
      Product code: A010-12AP

      Affinity purified rabbit polyclonal antibody to phospholamban phospho Ser-16. Made from product A010-12.

      • Suitable for use in Western blot (1:5000 dilution), IHC Microscopy (1:200 dilution)
      • Protein A affinity purified IgG (from polyclonal serum A010-12)
      • Species reactivity:  bovine, canine, ferret, hamster, human, rat and sheep.
      • 50 µl unit size
      Learn More
    3. Phospholamban (PLN, PLB) (pThr17) pAb serum

      $325.00
      Product code: A010-13

      Rabbit polyclonal anti-serum specific to Thr-17 phosphorylated forms of phospholamban.

      • Suitable for use in Western Blot (1:5000 dilution), IHC Microscopy (1:200 dilution)
      • Lyophilised anti-serum
      • Species recognition: all mammalian species, when phosphorylated on Thr-17
      • 25 μl unit size:
      Learn More
    4. Phospholamban (PLN, PLB) (pThr17) pAb

      $545.00
      Product code: A010-13AP

      Affinity purified rabbit polyclonal antibody specific to threonine-17 phosphorylated forms of phospholamban.  

      • Suitable for use in Western Blot (1:2000 dilution). 
      • Lyophilised affinity purified IgG. 
      • Species recognition: All mammalian species, when phosphorylated on threonine-17.
      • 100 μl  unit size
      Learn More
    5. SERCA2a pAb serum

      $325.00
      Product code: A010-20

      Rabbit polyclonal antibody to SERCA2a

      • Suitable for use in Western blot (1:5000 dilution)
      • Raw anti-serum IgG
      • Reacts with SERCA2a from human, rat, mouse, rabbit, canine, and bovine species
      • Unit Size: 20 µl
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    6. β-Dystroglycan (bDG) (pTyr892) pAb serum

      $325.00
      Product code: A010-200

      Lyophilised rabbit polyclonal anti-serum containing IgG antibody specific for Tyr-892 phosphorylated forms of β-dystroglycan

      • Suitable for use in Western blot (1:500 dilution), IHC Microscopy (1:50 dilution), Immunoprecipitation (1:10 dilution) in RIPA buffer.
      • Lyophilised antiserum.
      • Recognises β-dystroglycan in all mammalian species, when phosphorylated on Tyr-892 (or equivalent)
      • Unit size: 100 μl
      Learn More
    7. SERCA2 (pSer38) pAb

      $325.00
      Product code: A010-25AP

      Affinity purified polyclonal antibody specific to Ser-38 phosphorylated forms of SERCA2.

      • Suitable for use in Western Blot (1:1000 dilution)
      • Lyophilised affinity purified IgG
      • Species recognition: Epitope sequence exists in SERCA2 from all mammalian species
      • Unit size: 50 μl
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    8. Ryanodine receptor 2 (RYR2) (pSer2808) pAb serum

      $599.00
      Product code: A010-30

      Description: Rabbit Polyclonal anti-serum specific to RYR2 phospho Serine-2808.

      Unit Size: 50 µl

      Tested applications: Western blot (1:5000 dilution), IHC Microscopy (1:100 dilution)

      Antibody form: Lyophilised rabbit anti-serum (IgG).

      Species recognition: human, rat, mouse, rabbit, canine and sheep

      Learn More
    9. Ryanodine receptor 2 (RYR2) (pSer2808) pAb

      $655.00
      Product code: A010-30AP

      Polyclonal antibody specific to RYR2 phospho serine-2808.

      • Suitable for use in Western blot (1:2000 dilution)
      • Lyophilised Protein A affinity purified pntibody (IgG)
      • Species recognition: human, rat, mouse, rabbit, canine and sheep
      • 100 µl unit size
      Learn More
    10. Ryanodine receptor 2 (RYR2) (pSer2814) pAb serum

      $599.00
      Product code: A010-31

      Rabbit polyclonal antiserum specific to Ser-2814 phosphorylated RYR2

      • Suitable for use in Western blot (1:5000 dilution), IHC Microscopy (1:100 dilution)
      • Lyophilised rabbit anti-serum (IgG).
      • Species recognition: All mammalian species, when phosphorylated on Ser-2814 (or Ser-2815 rabbit) *
      • 50 µl unit size

      *Antibody recognises epitope despite single residue difference in epitope between species (V2815I; human vs mouse).

      Learn More

    Items 1 to 10 of 15 total

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    1. Clonality: pAb Remove This Item
    Category
    1. β-Dystroglycan (1)
    2. CaMK II (2)
    3. Phospholamban (PLN) (4)
    4. Ryanodine Receptor (6)
    5. SERCA (2)
    Product type
    1. Antibody (15)
    Target
    1. CaMKII (2)
    2. PLN (4)
    3. RyR2 (6)
    4. SERCA (1)
    5. SERCA2a (1)
    6. β-Dystroglycan (1)
    Phosphorylation site
    1. dephoSer2808 (1)
    2. pSer16 (2)
    3. pSer2030 (1)
    4. pSer2808 (2)
    5. pSer2814 (2)
    6. pSer38 (1)
    7. pThr17 (2)
    8. pThr286 or 287 (2)
    9. pTyr892 (1)
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    DISCLAIMER: Products for research use only (RUO) and are not intended for diagnostic or therapeutic use.

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