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    Cardiovascular Targets

    Cardiovascular Targets

    The excitation-contraction coupling of cardiac muscle is a critical to life in most animals, and errors in E-C coupling contribute to important human diseases (arrhythmia, heart failure, cardiac hypertrophy). Highly specific monoclonal and polyclonal antibodies to proteins critical to cardiac muscle excitation-contraction coupling have been assembled. All of these antibodies have been carefully validated for use in western blotting, in addition, some have also been validated for use in immunofluorescence microscopy and in vitro functional assays. Many of these antibodies recognise the site-specific phosphorylation of target proteins and most have been used in numerous publications in the scientific literature.

    Items 11 to 14 of 14 total

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    1. Ryanodine receptor 2 (RYR2) (pSer2030) pAb

      $629.00
      Product code: A010-32

       Polyclonal antibody specific to RYR2 phospho-Ser2030.

      • Suitable for use in Western blot (1:5000 dilution)
      • Antibody form: Lyophilised rabbit anti-serum (IgG)
      • Species recognition: human, rat, mouse, rabbit, canine and sheep
      • 50 µl unit size


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    2. Ryanodine receptor 2 (RYR2) (dephoSer2808) pAb

      $687.80
      Product code: A010-35AP

       Polyclonal antibody specific to Ser-2808 dephosphorylated RYR2

      • Suitable for use in Western blot (1:5000 dilution), IHC Microscopy (1:100)
      • Lyophilised rabbit anti-serum (IgG).
      • Species recognition: all mammalian species, when dephosphorylated on Ser-2808 (or 2809 rabbit)
      • 100 µl unit size
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    3. CaMKII (pThr286 or 287) pAb serum

      $341.30
      Product code: A010-50

      Polyclonal antibody specific to α and  β isoforms of CaMKII phospho-Thr286 (or Thr287 in β).

       

      • Suitable for use in  Western blot (1:5000 dilution)
      • Lyophilised Protein A Affinity Purified Antiboby (IgG).
      • Species Recognition: rat, human and mouse. Expected to react with various isoforms from chicken, cow, pig, rabbit, orangutan, zebrafish, ferret and Xenopus laevis.
      • 20 µl unit size


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    4. CaMKII (pThr286 or 287) pAb

      $341.30
      Product code: A010-50AP

      Polyclonal antibody specific to α isoform of CaMKII phospho-Thr286 (or Thr287 in β δ, γ isoforms of CaMKII) (CaMKII site).

      • Tested applications: Western blot (1:1000 dilution)
      •  Lyophilised Protein A Affinity Purified Antiboby (IgG).
      • Species Recognition: rat, human and mouse. Expected to react with various isoforms from chicken, cow, pig, rabbit, orangutan, zebrafish, ferret and Xenopus laevis.
      • 50 µl unit size
      Learn More

    Items 11 to 14 of 14 total

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    1. Clonality: pAb Remove This Item
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    1. CaMK II (2)
    2. Phospholamban (PLN) (4)
    3. Ryanodine Receptor (6)
    4. SERCA (2)
    Product type
    1. Antibody (14)
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    1. CaMKII (2)
    2. PLN (4)
    3. RyR2 (6)
    4. SERCA (1)
    5. SERCA2a (1)
    Phosphorylation site
    1. dephoSer2808 (1)
    2. pSer16 (2)
    3. pSer2030 (1)
    4. pSer2808 (2)
    5. pSer2814 (2)
    6. pSer38 (1)
    7. pThr17 (2)
    8. pThr286 or 287 (2)
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    DISCLAIMER: Products for research use only (RUO) and are not intended for diagnostic or therapeutic use.

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