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    Cardiovascular Targets

    Cardiovascular Targets

    The excitation-contraction coupling of cardiac muscle is a critical to life in most animals, and errors in E-C coupling contribute to important human diseases (arrhythmia, heart failure, cardiac hypertrophy). Highly specific monoclonal and polyclonal antibodies to proteins critical to cardiac muscle excitation-contraction coupling have been assembled. All of these antibodies have been carefully validated for use in western blotting, in addition, some have also been validated for use in immunofluorescence microscopy and in vitro functional assays. Many of these antibodies recognise the site-specific phosphorylation of target proteins and most have been used in numerous publications in the scientific literature.

    9 Item(s)

    1. SERCA2a pAb serum

      $325.00
      Product code: A010-20

      Rabbit polyclonal antibody to SERCA2a

      • Suitable for use in Western blot (1:5000 dilution)
      • Raw anti-serum IgG
      • Reacts with SERCA2a from human, rat, mouse, rabbit, canine, and bovine species
      • Unit Size: 20 µl
      Learn More
    2. SERCA1/2 mAb (clone Y/1F4)

      $325.00
      Product code: A010-21AP

       Affinity purified Mouse monoclonal antibody to SERCA isoforms 1/2

      • Suitable for use in Western blot (1:2000 dilution), IHC Microscopy (1:50 dilution).
      • Lyophilised Protein A affinity purified mouse monoclonal IgG
      • Tested on rat tissue, but immunogenic peptide aligns with Mammalian, Avian, Amphibian and Fish SERCA
      • Unit size: 50 μl
      Learn More
    3. SERCA1 mAb (clone B/4H3)

      $325.00
      Product code: A010-22AP
      Affinity purified Mouse monoclonal antibody to skeletal muscle SERCA1
      • Suitable for use in Western Blot (1:5000 dilution), IHC Microscopy (1:200 dilution)
      • Lyophilised Protein A affinity purified mouse monoclonal IgG
      • Antibody tested on rat and rabbit tissue, but immunogenic peptide aligns with mammalian species, avian, amphibian and fish
      • Unit size: 50 μl
      Learn More
    4. SERCA2a pAb serum

      $365.00
      Product code: A010-23L

      Rabbit antiserum containing IgG antibodies to SERCA2a protein

      • Suitable for use in WB (1:20,000 dilution)
      • Lyophilised rabbit serum.
      • Reatcs with all mammalian species 
      • Unit size: 20ul
      Learn More
    5. SERCA2a pAb serum

      $130.00
      Product code: A010-23S

      Rabbit antiserum containing IgG antibodies to SERCA2a protein.

      • Suitable for use in WB (1:20,000 dilution)
      • Lyophilised rabbit serum.
      • Reatcs with all mammalian species 
      • Unit size: 20ul
      Learn More
    6. SERCA2b pAb serum

      $365.00
      Product code: A010-24L

      Rabbit antiserum containing IgG antibodies specific to SERCA2b protein.

      • Suitable for use in WB (1:5,000 dilution)
      • Lyophilised rabbit serum (IgG)
      • Reacts with all mammalian species
      • 100ul unit size
      Learn More
    7. SERCA2b pAb serum

      $130.00
      Product code: A010-24S

      Rabbit antiserum containing IgG antibodies specific to SERCA2b protein.

      • Suitable for use in WB (1:5,000 dilution)
      • Lyophilised rabbit serum (IgG)
      • Reacts with all mammalian species
      • 20ul unit size
      Learn More
    8. SERCA2 (pSer38) pAb

      $325.00
      Product code: A010-25AP

      Affinity purified polyclonal antibody specific to Ser-38 phosphorylated forms of SERCA2.

      • Suitable for use in Western Blot (1:1000 dilution)
      • Lyophilised affinity purified IgG
      • Species recognition: Epitope sequence exists in SERCA2 from all mammalian species
      • Unit size: 50 μl
      Learn More
    9. Thapsigargin

      $84.00
      Product code: A010-503

      Potent inhibitor of sarco-endoplasmic reticulum Ca2+-ATPases. Causes ER stress; can be used to induce autophagy in mammalian cells.

      Learn More

    9 Item(s)

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    1. Category: SERCA Remove This Item
    Clonality
    1. mAb (2)
    2. pAb (6)
    Phosphorylation site
    1. pSer38 (1)
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    1. Antibody (8)
    2. Inhibitor (1)
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    1. SERCA (3)
    2. SERCA1 (1)
    3. SERCA2a (3)
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    DISCLAIMER: Products for research use only (RUO) and are not intended for diagnostic or therapeutic use.

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