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    Cardiovascular Targets

    Cardiovascular Targets

    The excitation-contraction coupling of cardiac muscle is a critical to life in most animals, and errors in E-C coupling contribute to important human diseases (arrhythmia, heart failure, cardiac hypertrophy). Highly specific monoclonal and polyclonal antibodies to proteins critical to cardiac muscle excitation-contraction coupling have been assembled. All of these antibodies have been carefully validated for use in western blotting, in addition, some have also been validated for use in immunofluorescence microscopy and in vitro functional assays. Many of these antibodies recognise the site-specific phosphorylation of target proteins and most have been used in numerous publications in the scientific literature.

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    1. L-type Ca2+ channel (Cav1.2) (pSer1928) pAb

      Product code: A010-70

      Polyclonal antibody specific to Ser-1928 phosphorylated Cav1.2 (α1c sub-unit of L-type Ca2+-channel).

      • Suitable for use in: IHC Microscopty (1:100 dilution)
      • Lyophilised rabbit anti-serum (IgG)
      • Species recognition: all mammalian species, when phosphorylated on Ser-1928.
      • Unit size: 50 µl
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    DISCLAIMER: Products for research use only (RUO) and are not intended for diagnostic or therapeutic use.

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