Exceptional, fully validated antibodies to CaMKII Phospho Threonine-286 (anti-CaMKII PT-286). Available as anti-sera or protein A affinity purified antibodies. Lyophilised with stabilizer for economical and environmentally friendly shipment and storage.
Ca2+/calmodulin-dependent protein kinases II or CaM kinases II are serine/threonine-specific protein kinases that are regulated by the Ca2+calmodulin complex. CaMKII is involved in many signaling cascades and is thought to be an important mediator of learning and memory. CaMKII is also necessary for Ca2+ homeostasis and reuptake in cardiomyocytes chloride transport in epithelia, positive T-cell selection, and CD8 T-cell activation. Misregulation of CaMKII is linked to Alzheimer’s disease, Angelman’s syndrome, and heart arrhythmia.
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