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    Ryanodine Receptor

    Ryanodine Receptor

    Badrilla provides a comprehensive range of research products to study ryanodine receptor function in health and disease. We have made the original and best antibodies to phosphorylated RYR2 (S2808, S2814, S2030). These are the most widely cited tools used by researchers to follow RYR2 phosphorylation at individual sites, and we display the citations for each antibody on the product page –data that are wholly independent of Badrilla and provided by CiteAb. Leaders in the field are confident of the quality of these antibodies as described in peer-reviewed articles available (Huke & Bers (2008) Biochem. Biophys. Res. Comm. 376, 80-85).

    We have bioactive peptides that mimic dysfunction ofRYR2 normally seen in CPVT-mutant channels(DPc10), fluorescent versions of these. These peptides turn a normal RYR2 channel into an abnormal (CPVT-like) channel and we may facilitate your exploration of disease conditions.

    5 Item(s)

    1. Caffeine

      $42.00
      Product code: A010-504
      Widely used pharmacological probe for studying ryanodine receptor (RyR)-mediated Ca2+ release and cardiac arrhythmias. Learn More
    2. Dantrolene sodium salt

      $67.00
      Product code: A010-505

      Dantrolene inhibits release of Ca2+ from the sarcoplasmic reticulum (SR) via inhibition of ryanodine receptor (RYR) channels. Learn More

    3. Ranolazine dihydrochloride

      $92.00
      Product code: A010-508

      Inhibits late sodium and potassium currents and blocks ligand binding to α1, β1, and β2 adrenergic receptors.

      Learn More
    4. Tetracaine hydrochloride

      $75.00
      Product code: A010-506

      Tetracaine inhibits the (Ca2+ + Mg2+)-ATPase from the sarcoplasmic reticulum.

      Learn More
    5. Thapsigargin

      $84.00
      Product code: A010-503

      Potent inhibitor of sarco-endoplasmic reticulum Ca2+-ATPases. Causes ER stress; can be used to induce autophagy in mammalian cells.

      Learn More

    5 Item(s)

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    1. Product type: Inhibitor Remove This Item
    Target
    1. RyR2 (4)
    2. SERCA (1)
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    Contact Us

    Leeds Innovation Centre

    103 Clarendon Road

    Leeds LS2 9DF

    United Kingdom

    +44 (0)7801 730618

    info@badrilla.com

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    DISCLAIMER: Products for research use only (RUO) and are not intended for diagnostic or therapeutic use.

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