DPc10 inactive peptide is a 36-residue peptide that differs from DPc10 (Gly2460-Pro2495, rabbit) at one position (R2475S) and represents the sequence of a known CPVT mutant RYR2 domain. This peptide binds weakly or fails to bind to the DPc10 interface and does NOT affect channel function. It serves as a negative control for research projects using DPc10 peptide.  

Pack size 200µg.

DPc10 peptide is a 36-residue peptide corresponding to the Gly2460-Pro2495 region of rabbit RyR2. It interacts with RYR2 and provokes abnormal channel activity usually seen in mutant RYR2 channels associated with CPVT. Elevates Ca2+-leak, increases Ca2+-spark activity, is pro-arrhythmic, and provokes hypertrophy in cardiac myocytes.  

Pack size 200µg.

Convenient, cost effective sampler pack containing four DPc10 peptide derivatives (200µg each) as follows:

1. DPc10 Peptide (Cat. A010-514)
2. DPc10 Inactive Peptide (Cat. A010-515)
3. Fluorescein DPc10 Peptide (Cat. A010-516)
4. Fluorescein DPc10 Inactive Peptide (Cat. A010-517)

Fluorescein derivative of DPc10 peptide, a 36-residue peptide corresponding to the Gly2460-Pro2495 region of rabbit RyR2. It interacts with RYR2 and provokes abnormal channel activity usually seen in mutant RYR2 channels associated with CPVT.  Elevates Ca2+-leak, increases Ca2+-spark activity, is pro-arrhythmic, and provokes hypertrophy in cardiac myocytes.

Pack size 200µg

 Polyclonal antibody specific to Ser-2808 dephosphorylated RYR2

• Suitable for use in Western blot (1:5000 dilution), IHC Microscopy (1:100)
• Lyophilised rabbit anti-serum (IgG).
• Species recognition: all mammalian species, when dephosphorylated on Ser-2808 (or 2809 rabbit)
• 100 µl unit size

 Polyclonal antibody specific to RYR2 phospho-Ser2030.

• Suitable for use in Western blot (1:5000 dilution)
• Antibody form: Lyophilised rabbit anti-serum (IgG)
• Species recognition: human, rat, mouse, rabbit, canine and sheep
• 50 µl unit size

Polyclonal antibody specific to RYR2 phospho serine-2808.

• Suitable for use in Western blot (1:2000 dilution)
• Lyophilised Protein A affinity purified pntibody (IgG)
• Species recognition: human, rat, mouse, rabbit, canine and sheep
• 100 µl unit size

Description: Rabbit Polyclonal anti-serum specific to RYR2 phospho Serine-2808.

Unit Size: 50 µl

Tested applications: Western blot (1:5000 dilution), IHC Microscopy (1:100 dilution)

Antibody form: Lyophilised rabbit anti-serum (IgG).

Species recognition: human, rat, mouse, rabbit, canine and sheep

Affinity purified rabbit polyclonal antibody specific to Ser-2814 phosphorylated RYR2.

• Suitable for use in Western blot (1:500 dilution)
• Lyophilised Protein A affinity purified antibody (IgG)
• Unit Size: 400 µg
• Species recognition: all mammalian species, when phosphorylated on Ser-2814 (or Ser-2815 rabbit) 

Antibody recognises epitope despite single residue difference in epitope between species (V2815I; human vs mouse).