• My Basket 0

    Badrilla Default welcome msg!

    Back

    Oxidative Stress and Heart Failure

    Oxidative Stress and Heart Failure

    Oxidative stress plays an important role in heart failure

    Age-related decline of cardiac performance is often associated with oxidative stress and increased levels of free radicals, encompassing both reactive oxygen (ROS) and nitrogen species (RNS).  Formation of RNS species is reported in acute myocardiac disorders such as heart failure. These species are metabolites and/or oxidation products of nitrogen monoxide (NO), such as nitrogen dioxide (NO2) and peroxynitrite (ONOO). A hallmark of these species is the conversion of tyrosine to 3-nitrotyrosine (3-NY).  

    Further reading: Oxidative stress and heart failure. Am J Physiol Heart Circ Physiol. 2011 Dec;301(6):H2181-90 [PubMed]

    Which tools do I need? Badrilla is pleased to offer a high integrity monoclonal antibodies and Western blotting starter packs for nitrotyrosine.  Ideal reagents for use in the evaluation of oxidative stress in cardiac samples.

    3 Item(s)

    1. Nitrotyrosine mAb (clone 2E11)

      $325.00
      Product code: A010-2E11

      Affinity purified mouse monoclonal antibody clone 2E11 to nitrotyrosine

      • Suitable for use in Western blot (1:2000 dilution)
      • Antibody Form: IgG2b
      • Protein A affinity purified
      • Reacts with Nitrotyrosine either free or incorporated in proteins such as human serum nitro albumin, nitro haemoglobin and nitro insulin. All species
      • Unit size: 50 µl
      Learn More
    2. Nitrotyrosine Western blot starter pack

      $420.00
      Product code: A010-513

      A convenient reagent pack containing a high integrity nitrotyrosine monoclonal antibody and associated positive and negative controls.

      Learn More
    3. Nitrotyrosine mAb (Clone 6B2)

      $325.00
      Product code: A010-6B2AP

       Affinity purified Mouse monoclonal antibody clone 6B2 to NitroTyrosine (NY)

      • Suitable for use in Western blot (1:5000 dilution)
      • Protein A affinity purified
      • Reacts with Nitrotyrosine either free or incorporated in proteins such as human serum nitro albumin, nitro haemoglobin and nitro insulin. All species
      • Unit Size: 20 µl
      Learn More

    3 Item(s)

    Shop By
    Product type
    1. Antibody (3)
    Target
    1. Nitrotyrosine (3)
    Clonality
    1. mAb (3)
    Compare

    You have no items to compare.

    Contact Us

    Leeds Innovation Centre

    103 Clarendon Road

    Leeds LS2 9DF

    United Kingdom

    +44 (0)7801 730618

    info@badrilla.com

    Useful Links

    .

    DISCLAIMER: Products for research use only (RUO) and are not intended for diagnostic or therapeutic use.

    Badrilla Newsletters

    Sign up for Badrilla newsletters today and receive twice-monthly informative emails relating to cardiovascular research.
    Badrilla enewsletter sign up