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    S-Nitrosylation Tools

    S-Nitrosylation Tools

    Nitric oxide (NO) plays an important role in the regulation of cardiovascular function. In addition to the classic NO activation of the cGMP-dependent pathway, NO can also regulate cell function through protein S-nitrosylation, a redox dependent, thiol-based, reversible posttranslational protein modification that involves attachment of an NO moiety to a nucleophilic protein sulfhydryl group.

    A better understanding of the mechanisms regulating protein S-nitrosylation will provide us new therapeutic insights and targets for intervention in cardiovascular disease. Badrilla offers a growing range of antibodies and detection kits to support your nitric oxide and S-nitrosylaltion research projects; further details for each of these products can be found below.

    4 Item(s)

    1. DETECTome™ S-nitrosylated protein kit

      $368.00
      Product code: A010-105
      A convenient and easy-to-use kit incorporating a modification of the “biotin-switch” method to allow for the direct visualisation of S-nitrosylated proteins in whole cells or tissues, as well as by western blot analysis. 
       
      • A modified ‘biotin-switch’ assay
      • Labels all S-nitrosylated sites in sample ('omics')
      • DETECT S-NO proteins in whole cells, tissues or lysates
      • Colourimetric or fluorimetric detection
      • Sufficient reagents for 3 x 20 samples
      Learn More
    2. Nitrotyrosine mAb (clone 2E11)

      $325.00
      Product code: A010-2E11

      Affinity purified mouse monoclonal antibody clone 2E11 to nitrotyrosine

      • Suitable for use in Western blot (1:2000 dilution)
      • Antibody Form: IgG2b
      • Protein A affinity purified
      • Reacts with Nitrotyrosine either free or incorporated in proteins such as human serum nitro albumin, nitro haemoglobin and nitro insulin. All species
      • Unit size: 50 µl
      Learn More
    3. Nitrotyrosine mAb (Clone 6B2)

      $325.00
      Product code: A010-6B2AP

       Affinity purified Mouse monoclonal antibody clone 6B2 to NitroTyrosine (NY)

      • Suitable for use in Western blot (1:5000 dilution)
      • Protein A affinity purified
      • Reacts with Nitrotyrosine either free or incorporated in proteins such as human serum nitro albumin, nitro haemoglobin and nitro insulin. All species
      • Unit Size: 20 µl
      Learn More
    4. Nitrotyrosine Western blot starter pack

      $420.00
      Product code: A010-513

      A convenient reagent pack containing a high integrity nitrotyrosine monoclonal antibody and associated positive and negative controls.

      Learn More

    4 Item(s)

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    Clonality
    1. mAb (3)
    Product type
    1. Antibody (3)
    2. Detection kit (1)
    Target
    1. Nitrotyrosine (3)
    2. S-NO (1)
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    DISCLAIMER: Products for research use only (RUO) and are not intended for diagnostic or therapeutic use.

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