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    S-Nitrosylation Tools

    S-Nitrosylation Tools

    Nitric oxide (NO) plays an important role in the regulation of cardiovascular function. In addition to the classic NO activation of the cGMP-dependent pathway, NO can also regulate cell function through protein S-nitrosylation, a redox dependent, thiol-based, reversible posttranslational protein modification that involves attachment of an NO moiety to a nucleophilic protein sulfhydryl group.

    A better understanding of the mechanisms regulating protein S-nitrosylation will provide us new therapeutic insights and targets for intervention in cardiovascular disease. Badrilla offers a growing range of antibodies and detection kits to support your nitric oxide and S-nitrosylaltion research projects; further details for each of these products can be found below.

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    1. CAPTUREome™ S-Palmitoylated Protein Kit

      Product code: K010-311

      The Badrilla CAPTUREomeTM S-Palmitoylated protein kit is a simple and easy way of determining whether your protein of interest is post translationally modified with a palmitate group. The assay is based on the acyl-RAC (resin assisted capture) method and facilitates, with four simple steps – Block, Cleave, Capture and Analysis -  determination of protein palmitoylation.

      Kit highlights

      • Enables capture of S-palmitoylated proteins.
      • Kit designed to process 4 x 5 biological samples with paired negative controls (i.e. 40 samples in total).
      • Convenient stopping point after blocking treatment.
      • Assay suitable for downstream SDS-PAGE, western blot or mass spectrometry analysis.
      Learn More

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    DISCLAIMER: Products for research use only (RUO) and are not intended for diagnostic or therapeutic use.

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