Rabbit polyclonal antiserum containing antibodies (IgG) specific for Ser-2814 (CaMKII) phosphorylated RYR2.
Synthetic peptide (TSQVS(PO3H2)VDAAH2819) corresponding to amino acids surrounding the phosphorylated serine residue at position 2814 of RyR2 (human) conjugated to KLH.
Antibody in this antiserum recognises phosphorylated serine 2814 of the ryanodine receptor in many species (dog, mouse, rat, rabbit, human). The epitope sequence used corresponds exactly in rabbit but differs at one residue (V2815I) in mouse and rat. However, the antibody recognises both sequences. Recognises Ser-2814 phosphorylated RYR2 exclusively, and will not react with dephosphorylated RYR2 or other forms of phosphorylated RYR2.
Lyophilised antibody is stable at 4°C when stored with desiccant. Reconstitute lyophilised powder in 50 µl of 18 MΩ H2O, aliquot and store frozen at -80°C for 1 year. Avoid freeze – thaw cycles. Lyophilised: 4 °C Reconstituted:-80 °C
Product for research use only. Not intended for diagnostic or therapeutic use.